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. 2019 Oct 23;318(2):L421–L428. doi: 10.1152/ajplung.00316.2019

Fig. 2.

Fig. 2.

Germ-free (GF) animals have better lung mechanics than non–germ-free (NGF) animals in hyperoxia. A: total lung resistance was similar between NGF and GF normoxia pups. Hyperoxia significantly increased lung resistance in NGF pups compared with normoxia NGF pups. However, lung resistance was not increased in hyperoxia GF pups compared with GF normoxia pups. GF hyperoxia pups had decreased lung resistance compared with NGF hyperoxia pups. B: lung compliance was decreased in the hyperoxia NGF group; however, GF pups did not show reduction in lung compliance after hyperoxia exposure. GF hyperoxia pups had increased lung compliance compared with NGF hyperoxia pups. Data are means ± SE; n = 5–7 animals per group. *P < 0.05, **P < 0.01, ***P < 0.001. PN14, postnatal day 14.