Table 4. Differences in Pain Interference Domains at Study Completion by Treatment Group.
| Pain Interference at Visit 6 | Estimate (SE) | z Value | P Value |
|---|---|---|---|
| Overall mean interference | |||
| Placebo | 2.21 (0.26) | ||
| Pregnenolone | 1.84 (0.23) | ||
| Difference | 0.83 (0.14) | −1.12 | .26 |
| Mood | |||
| Placebo | 2.18 (0.33) | ||
| Pregnenolone | 1.75 (0.29) | ||
| Difference | 0.80 (0.17) | −1.02 | .31 |
| Work | |||
| Placebo | 2.44 (0.28) | ||
| Pregnenolone | 1.74 (0.23) | ||
| Difference | 0.71 (0.12) | −2.05 | .04 |
| Sleep | |||
| Placebo | 2.39 (0.30) | ||
| Pregnenolone | 2.38 (0.31) | ||
| Difference | 0.99 (0.17) | −0.05 | .96 |
| Activity | |||
| Placebo | 2.88 (0.32) | ||
| Pregnenolone | 2.04 (0.26) | ||
| Difference | 0.71 (0.11) | −2.15 | .03 |
| Walking | |||
| Placebo | 1.79 (0.26) | ||
| Pregnenolone | 1.86 (0.25) | ||
| Difference | 1.03 (0.20) | 0.17 | .86 |
| Relationships | |||
| Placebo | 1.45 (0.30) | ||
| Pregnenolone | 1.18 (0.20) | ||
| Difference | 0.82 (0.18) | −0.91 | .36 |
| Enjoyment | |||
| Placebo | 2.20 (0.26) | ||
| Pregnenolone | 1.85 (0.30) | ||
| Difference | 1.85 (0.30) | −0.99 | .32 |