Summary of findings for the main comparison. 'As required' medication versus regular timed medication for seriously mentally ill people in hospital.

'As required' medication versus regular timed medication for seriously mentally ill people in hospital
Patient or population: seriously mentally ill people in hospital Settings: Hospital Intervention: 'as required' medication versus regular timed medication
Outcomes	Illustrative comparative risks* (95% CI)		Relative effect (95% CI)	No of participants (studies)	Quality of the evidence (GRADE)
	Assumed risk	Corresponding risk
	Control	'As required' medication versus regular timed medication
Mental state: important change in mental state	We found no trial‐based evidence to support or refute use of 'as required' medication as opposed to regular timed doses Our summary of the findings is, therefore, that there are no data to guide practice from trials for these key outcomes for a situation that is commonly encountered in routine care
Behaviour: important change in behaviour
Behaviour: aggression
Dosage: important difference in dose used
Adverse events: important adverse events
Satisfaction with care: important change in satisfaction with care
Cost: important change in cost