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. 2020 Feb 19;7(3):ofaa054. doi: 10.1093/ofid/ofaa054

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© The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 1. — Participants with protocol-defined nephrotoxicity or AKI by KDIGO or RIFLE criteria. If the patient met criteria for >1 AKI stage, they were only included once, in the worst-case stage. ^aTwo participants in the IMI/REL group with missing creatinine values were excluded from the nephrotoxicity and AKI evaluations.Abbreviations: AKI, acute kidney injury; IMI, imipenem/cilastatin; IMI/REL, imipenem/cilastatin plus relebactam; KDIGO, Kidney Disease: Improving Global Outcomes; RIFLE, Risk, Injury, Failure, Loss, and End-stage Kidney Disease.