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. 2008 Jan 23;2008(1):CD000038. doi: 10.1002/14651858.CD000038.pub2

Platt 1985.

Methods Quasi‐randomisation using sequential numbers (even/odd).
Participants 642 women with high‐risk pregnancies, ie post‐term (41%), IUGR (13%), diabetes (12%), decreased fetal movements (7%), hypertension (12%), previous stillbirth (3%). 279 women were randomised to a BPP and 373 to the control group. Mean gestational age 39 weeks.
Interventions BPP versus CTG (non‐stress test). 
 Experimental group: BPP twice weekly. 
 Control group: CTG and ultrasound measurement of the maximum pool depth twice weekly. 
 If monitoring was normal, labour was induced at 43 weeks. Abnormal monitoring was an indication for induction of labour as soon as possible.
Outcomes Perinatal death (> 500 gr, < 28 day of life). 
 Intrapartum fetal distress (persistent late decelerations, bradycardia or serial fetal scalp sampling with pH < 7.20, or both. 
 Apgar < 7 after 5 minutes 
 Birthweight below 10th centile.
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) High risk C ‐ Inadequate

AFI: amniotic fluid index 
 BPP: biophysical profile 
 CTG: cardiotocography 
 FBM: fetal breathing movements 
 FM: fetal movements 
 FT: fetal tone 
 IUGR: intrauterine growth retardation 
 MBPP: modified biophysical profile