Table 1.
Number of Pediatric CNS Tumors by Major Histology Grouping and Age Group at Diagnosis During the Period 2001–2015 in Canada
| Histology | Age at Diagnosis | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 0–14 years | 0–4 years | 5–9 years | 10–14 years | ||||||
| Mean age (95% CI) | n | IR | n | IR | n | IR | n | IR | |
| Low-grade glioma | 6.93 (6.69–7.17) | 1203 | 1.41 | 402 | 1.48 | 412 | 1.46 | 389 | 1.29 |
| High-grade glioma | 6.36 (6.07–6.65) | 736 | 0.86 | 278 | 1.02 | 265 | 0.94 | 193 | 0.64 |
| Embryonal tumors | 5.46 (5.15–5.77) | 619 | 0.72 | 292 | 1.07 | 213 | 0.76 | 114 | 0.38 |
| Medulloblastoma | 6.25 (5.90–6.60) | 425 | 0.50 | 158 | 0.58 | 177 | 0.63 | 90 | 0.30 |
| PNET | 5.38 (4.59–6.17) | 114 | 0.13 | 61 | 0.22 | 29 | 0.10 | 24 | 0.08 |
| ATRT | 1.39 (0.98–1.80) | 80 | 0.09 | 73 | 0.27 | 7 | 0.03 | 0 | 0.00 |
| Ependymoma malignant | 4.70 (4.18–5.23) | 247 | 0.29 | 152 | 0.56 | 48 | 0.17 | 47 | 0.16 |
| Other tumors | 6.04 (5.45–6.64) | 245 | 0.25 | 118 | 0.38 | 50 | 0.15 | 77 | 0.23 |
| Craniopharyngioma | 8.36 (7.76–8.97) | 143 | 0.17 | 23 | 0.08 | 64 | 0.23 | 56 | 0.19 |
| Malignant germ cell | 9.73 (9.02–10.45) | 113 | 0.13 | 13 | 0.05 | 28 | 0.10 | 72 | 0.24 |
| Total | 6.49 (6.31–6.60) | 3306 | 3.80 | 1278 | 4.65 | 1080 | 3.79 | 948 | 3.11 |