TABLE 1.

Intra-day (n = 6) and inter-day (n = 18) precision and accuracy for QC samples of GDC-0084 in human plasma and CSF

			Intra-day			Inter-day
	Nominal (ng/mL)	Mean Concentration (ng/mL)	%CV	%Accuracy	Mean Concentration (ng/mL)	%CV	%Accuracy
Human Plasma	0.2	0.208	1.4	104.0	0.211	4.2	105.5
	0.5	0.520	1.4	104.0	0.530	3.2	105.8
	10	10.3	3.2	103.0	10.7	4.6	107.0
	160	157	1.8	98.1	161	3.9	100.6
Human CSF	0.2	0.209	4.0	104.5	0.189	9.3	94.5
	0.5	0.494	1.7	98.8	0.469	4.7	93.8
	10	9.84	1.4	98.4	9.70	2.1	97.0
	160	156	1.2	97.5	154	2.0	96.3

CV, coefficient of variation.