Comparison 30. Methods ‐ combined control group versus twice counting tx.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Twice counting ‐ short‐acting antibiotic > 48 hours short‐term treatment, treatment failure at 1 month or less	9	2249	Peto Odds Ratio (Peto, Fixed, 95% CI)	1.43 [1.14, 1.79]
2 Combined control groups ‐ short‐acting antibiotic > 48 hours short‐term treatment, treatment failure 1 month or less	9	2611	Peto Odds Ratio (Peto, Fixed, 95% CI)	1.36 [1.10, 1.67]
3 Twice counting ‐ short‐acting antibiotic > 48 hours short‐term treatment, treatment failure at 1 to 19 days	4	1138	Peto Odds Ratio (Peto, Fixed, 95% CI)	1.52 [1.11, 2.10]
4 Combined control groups ‐ short‐acting antibiotic > 48 hours short‐term treatment, treatment failure 1 to 19 days	4	1327	Peto Odds Ratio (Peto, Fixed, 95% CI)	1.45 [1.08, 1.95]
5 Twice counting ‐ short‐acting antibiotic > 48 hours short‐term treatment, treatment failure 20 to 30 days	7	1632	Peto Odds Ratio (Peto, Fixed, 95% CI)	1.26 [0.97, 1.64]
6 Combined control groups ‐ short‐acting antibiotic > 48 hours short‐term treatment, treatment failure at 20 to 30 days	7	1805	Peto Odds Ratio (Peto, Fixed, 95% CI)	1.22 [0.95, 1.57]
7 Twice counting ‐ short‐acting antibiotic > 48 hours short‐term treatment, treatment failure at 30 to 40 days	2	538	Peto Odds Ratio (Peto, Fixed, 95% CI)	1.07 [0.74, 1.55]
8 Combined control groups ‐ short‐acting antibiotic > 48 hours short‐term treatment, treatment failure 30 to 40 days	2	686	Peto Odds Ratio (Peto, Fixed, 95% CI)	1.12 [0.80, 1.57]
9 Twice counting ‐ short‐acting antibiotic > 48 hours short‐term treatment, treatment failure at 3 months or less	4	745	Peto Odds Ratio (Peto, Fixed, 95% CI)	1.10 [0.80, 1.50]
10 Combined control groups ‐ short‐acting antibiotic > 48 hours short‐term treatment, treatment failure at 3 months or less	4	893	Peto Odds Ratio (Peto, Fixed, 95% CI)	1.13 [0.85, 1.51]