| Methods |
Double‐blind, placebo‐controlled, RCT |
| Participants |
US children aged 6 months to 12 years |
| Interventions |
Single dose of 30 mg/kg azithromycin
versus
amoxicillin/clavulanate 45 mg/kg twice daily for 10 days |
| Outcomes |
Absence or improvement of signs and symptoms on day 12 to 16 and day 28 to 32 |
| Notes |
— |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Blinding (performance bias and detection bias)
Treatment failure at 1 month or less |
Low risk |
|
| Incomplete outcome data (attrition bias)
Treatment failure at 1 month or less |
Low risk |
|
| Selective reporting (reporting bias) |
Low risk |
|
| Other bias |
Unclear risk |
Industry funding |
