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. 2010 Sep 8;2010(9):CD001095. doi: 10.1002/14651858.CD001095.pub2

Chamberlain 1994.

Methods RCT
Participants Children 18 months to 6 years old in Washington, DC
Interventions Ceftriaxone 50 mg/kg intramuscularly x one dose 
 versus 
 cefaclor 40 mg/kg/day for 10 days
Outcomes Absence or improvement of symptoms, and normal or improved tympanogram at 7 to 10 days and monthly for 90 days after study entry
Notes
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk  
Blinding (performance bias and detection bias) 
 Treatment failure at 1 month or less Low risk  
Selective reporting (reporting bias) Low risk  
Other bias Low risk Industry funding