Chamberlain 1994.
Methods | RCT | |
Participants | Children 18 months to 6 years old in Washington, DC | |
Interventions | Ceftriaxone 50 mg/kg intramuscularly x one dose versus cefaclor 40 mg/kg/day for 10 days | |
Outcomes | Absence or improvement of symptoms, and normal or improved tympanogram at 7 to 10 days and monthly for 90 days after study entry | |
Notes | — | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | |
Blinding (performance bias and detection bias) Treatment failure at 1 month or less | Low risk | |
Selective reporting (reporting bias) | Low risk | |
Other bias | Low risk | Industry funding |