| Methods |
Randomised controlled, double‐blind trial |
| Participants |
British multicentre trial of children 2 to 10 years old |
| Interventions |
Amoxicillin 125/250 mg 3 times daily for 3 days + placebo for
7 days versus
amoxicillin 125/250 mg 3 times daily for 10 days |
| Outcomes |
Resolution of signs and symptoms at 13 to 16 days after and recurrence within 12 weeks of study entry |
| Notes |
— |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Blinding (performance bias and detection bias)
Treatment failure at 1 month or less |
Low risk |
|
| Incomplete outcome data (attrition bias)
Treatment failure at 1 month or less |
Low risk |
|
| Selective reporting (reporting bias) |
Low risk |
|
| Other bias |
Low risk |
|
