Hoberman 2005.
Methods | Investigator blinded, randomized controlled multicentre trial | |
Participants | Multicentre trial of children 6 to 30 months of age in various countries | |
Interventions | Azithromycin 10 mg/kg for 1 day followed by 5 mg/kg/d for 5 days versus amoxicillin/clavulanate 90/6.4 mg/kg/d in 2 divided doses for 10 days | |
Outcomes | Absence or improvement of signs and symptoms at day 4 to 6, 12 to 14 and 21 to 25 days after study entry | |
Notes | — | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Blinding (performance bias and detection bias) Treatment failure at 1 month or less | Unclear risk | Investigator blinded |
Selective reporting (reporting bias) | Low risk | |
Other bias | Low risk | Industry funding |