| Methods |
Randomised controlled, double‐blind trial |
| Participants |
US multicentre trial of children 1 to 15 years old |
| Interventions |
Azithromycin 5 to 10 mg/kg once daily/placebo twice daily for 5 days + placebo 3 times daily for 5 days versus
amoxil‐clavulanate 40 mg/kg/day 3 times daily for 10 days |
| Outcomes |
Absence or improvement of signs and symptoms at 11 days and 30 days after study entry |
| Notes |
— |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Blinding (performance bias and detection bias)
Treatment failure at 1 month or less |
Low risk |
|
| Incomplete outcome data (attrition bias)
Treatment failure at 1 month or less |
High risk |
|
| Selective reporting (reporting bias) |
Low risk |
|
| Other bias |
Unclear risk |
Funding not reported |
