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. 2010 Sep 8;2010(9):CD001095. doi: 10.1002/14651858.CD001095.pub2

Ploussard 1984.

Methods RCT
Participants Children 5 months to 5 years old in Alabama, US
Interventions Cefaclor 40 mg/kg 3 times daily for 5 days 
 versus 
 amoxicillin 40 mg/kg 3 times daily for 10 days
Outcomes Absence or improvement of signs and symptoms at 10 to 16 days after study entry
Notes
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk  
Blinding (performance bias and detection bias) 
 Treatment failure at 1 month or less High risk  
Incomplete outcome data (attrition bias) 
 Treatment failure at 1 month or less Low risk  
Selective reporting (reporting bias) Low risk  
Other bias Unclear risk Funding not reported