Principi 1995.

Methods	RCT
Participants	Multicentre trial (Europe, South America) of children 6 months to 12 years old
Interventions	Azithromycin 10 mg/kg once daily for 3 days versus amoxil‐clavulanate 40 mg/kg 3 times daily for 10 days
Outcomes	Absence or improvement of signs and symptoms at 10 to 14 days after study entry
Notes	—
Risk of bias
Bias	Authors' judgement	Support for judgement
Blinding (performance bias and detection bias) Treatment failure at 1 month or less	High risk
Incomplete outcome data (attrition bias) Treatment failure at 1 month or less	Low risk
Selective reporting (reporting bias)	Low risk
Other bias	Unclear risk	Funding not reported