Marneros 1979.

Methods	Allocation: randomised; no further details. Blindness: double. Design: parallel. Duration: 21 days (short‐term trial duration). Location: not indicated. Setting: inpatients.
Participants	Diagnosis: schizophrenia (criteria of K. Schneider). History: acute exacerbation. N = 20. Age: 20‐55 years. Sex: not indicated.
Interventions	1. Camazepam: dose 40 mg/d + haloperidol 12 mg/d. N = 10. 2. Placebo + haloperidol: dose 12 mg/d. N = 10.
Outcomes	Leaving the study early. Unable to use: Global state: CGI (incomplete numbers).
Notes	Adjunctive treatment with benzodiazepine was significantly better in affective symptoms, like aggression etc.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	No randomisation mentioned in the publication, but the trial was described as “double‐blind.” Thus it was implied that the study was randomised.
Allocation concealment (selection bias)	Unclear risk	No further details.
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	“Double‐blind”, no further details.
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	“Double‐blind”, no further details.
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	Three patients in the camazepame group left the trial early (30%) and no participant in the placebo group; the total number of patients leaving the trial early is moderate (15%). The trial authors provided the individual patient data.
Selective reporting (reporting bias)	High risk	The outcomes that are of interest in the review were not fully addressed. The adverse effects were not fully addressed.
Other bias	Unclear risk	Insufficient information to assess whether an important risk of bias exists.