Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Feb 3;10(6):2849–2858. doi: 10.7150/thno.41566

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The author(s)

This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.

PMC Copyright notice

Nanodroplet characterization: (A) schematic of drug-loaded lipid shell composed of 1,2-dihexadecanoyl-sn-glycero-3-phosphate (DPPA), 1,2-dipalmitoryl-sn-glycero-3-phosphoethanolamine conjugated polyethylene glycol (MPEG5000 DPPE) and 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), (B) nanodroplet size distribution by nanoparticle tracking analysis at 1:10 dilution (n=3) with example brightfield image (scale bar 10 μm), (C) resultant microbubble size distribution measured by Coulter Counter (n=3) with example brightfield image (scale bar 10 μm), (D) spontaneous drug release measured in storage conditions of 4°C, 23°C, 37°C, (E) acoustic vaporization threshold in vitro shown through ultraharmonic emissions (black) alongside percentage of pentobarbital released (red) at increasing sonication pressures (n=6), (F) and comparison of vaporization pressures in vitro and in vivo (n=8), error bars show one standard deviation.