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. 2020 Feb 3;10(6):2696–2713. doi: 10.7150/thno.41001

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Identification and validation of the 2-gene signature predictive of the presence of VDAC1-ΔC and the primary cilium of ccRCC patients from 19 ccRCC patients. A, The mRNA (2-gene signature) and immunofluorescence (Acetyl. a-Tubulin, Arl13b and DAPI) of tumors samples of 12 patients were studied to evaluate the prediction model of the absence or presence of the primary cilium. Normal tissues (N) and tumoral tissues (T). B, Representative image of immunohistochemistry (IHC) analysis of the 19 patients studied to evaluate a prediction model of the absence or presence of the primary cilium. C, Percentage of ciliated cells in normal and tumor tissues from patients. A *** p<0.0005 show significant differences.