Table 1.
Patient Information and Dosimetric Parameters
| Histology/ Stage | Patients (n) | Median | Percentage/ Range | |
|---|---|---|---|---|
| Male | 102 | 86·5% | ||
| Female | 16 | 13·5% | ||
| Age | 60 years | 36-79 years | ||
| Histology | squamous | 41 | 34·7% | |
| adeno | 19 | 16·1% | ||
| small cell | 53 | 44·9% | ||
| other | 5 | 4·2% | ||
| Stage | I-II | 7 | 5·9% | |
| III | 86 | 72·9% | ||
| IV | 25 | 21·2% | ||
| Smoker | 97 | 82·2% | ||
| Non-smoker | 21 | 17·8% | ||
| COPD | 40 | 33·9% | ||
| With former surgery | 10 | 8·5% | ||
| With chemotherapy or targeted therapy | 114 | 96·6% | ||
| Primary tumor dose | 61·6 Gy | 30-70 Gy | ||
| MLD | 11·6 Gy | 3.3-19 Gy | ||
| V30 | 12·0% | 2·0%-23·1% | ||
| V20 | 20·0% | 2·0%-30·5% | ||
| V10 | 34·2% | 4·0%-60·0% | ||
| V5 | 51·0% | 13·8%-86·0% | ||
| Follow-up time | 314 days | 37-614 days | ||
| RP grade≥2 patient | 50 | 42·4% | ||
| median interval to RP grade≥2 diagnosis | 86 days | 33-205 days |
COPD= chronic obstructive pulmonary disease; MLD= mean lung dose in Gy; V30, V20, V10, V5= the percentage of the lung volume (with subtraction of the volume involved by lung cancer) which receives radiation doses of 30, 20, 10, 5 Gy or more.