Table 2.
statistical comparison of the clinic parameters between patients with and without G≥2 radiation pneumonitis
Patients with RP≥2 (need clinical interventions) |
Patients with RP<2 or no RP (do not need clinical interventions) |
p-value | |||
---|---|---|---|---|---|
Patients (n) | 50 | 68 | N/A | ||
Male (percentage) | 41(82.0%) | 61 (89.7%) | 0.2803 | ||
Female (percentage) | 9 (18.0%) | 7 (10.3%) | |||
Age (median) | 46-79 (61) | 36-77 (58) | 0.08805 | ||
Histology | Non-small cell | 25 (50.0%) | Non-small cell | 35 (51.5%) | 0.3102 |
small cell | 20 (40.0%) | small cell | 31 (45.6%) | ||
other | 5 (10%) | other | 2 (2.9%) | ||
Stage | I-II | 3 (6.0%) | I-II | 3 (4.4%) | 0.946 |
III | 36 (72%) | III | 50 (73.5%) | ||
IV | 11 (22%) | IV | 15 (22.1%) | ||
Smoker | 10 (20.0%) | 11 (16.2%) | 0.6319 | ||
Non-smoker | 40 (80.0%) | 57 (83.8%) | |||
With COPD | 20 (40.0%) | 20 (29.4%) | 0.2444 | ||
KPS | 80-90(88.6) | 70-90(88.38) | 0.7955 | ||
With former chest surgery | 9 (18.0%) | 1 (1.5%) | 0.001854 | ||
With chemotherapy or targeted therapy | 49 (98.0%) | 64 (94·1%) | 0.5647 |
COPD= chronic obstructive pulmonary disease; KPS= Karnofsky Performance Scale.