Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
MSC-derived IL-6 induces CD73 expression, activates STAT3 signaling pathway and promotes tumor growth. a. The expression of CD73, IL-6, gp130, gp80, STAT3, p-STAT3, PCNA, Bax, Bcl-2, MMP-9, Vimentin, SOX-2, α-SMA were detected by western blot analysis. Luciferase activity imaging of tumor-bearing mice (b). Mice were euthanized and tumor volumes and weight were measured (c). *, P < 0.05; P=0.0675 (tumor volume: MSCIL6KO vs MSC); P=0.0960 (tumor weight: MSCIL6KO vs MSC)
