Pathway analyzed with DIANA-mirpath and circRNA-miRNA-mRNA interaction networks. (A1) 6 genes were involved in the three pathways simultaneously. Proteoglycans, adherens junction, and signaling pathways regulating pluripotency of stem cells were analyzed with DIANA-mirpath. (A2) 7 miRNAs were simultaneously involved in the three pathways from the 100 miRNAs including the top 20 miRNAs (ranked by fold change) which restored the expression of circRNAs. (B) The circRNA-miRNA-mRNA interaction network involving the three pathways, 6 genes, 7 circRNAs, and 7 corresponding miRNAs.