Table 1.
Hub genes in the midnightblue module related with CRC recurrence
| Gene symbol | Probe | cor.geneModuleMembership | Hub gene in PPI network | DEG analysis | |
|---|---|---|---|---|---|
| |logFC| | FDR | ||||
| MYL9 | 201058_s_at | 0.943041082 | Yes | 1.617677 | 1.03E-14 |
| MYLK | 202555_s_at | 0.936476159 | Yes | 1.794758 | 7.82E-19 |
| CNN1 | 203951_at | 0.906218239 | Yes | 2.713818 | 1.34E-19 |
| DES | 202222_s_at | 0.841739696 | Yes | 2.55989 | 7.76E-18 |
| HSPB8 | 221667_s_at | 0.913958361 | No | 2.087421 | 3.09E-27 |
| SPARCL1 | 200795_at | 0.900690649 | No | 1.531813 | 3.86E-21 |
| KCNMB1 | 209948_at | 0.890620367 | No | 1.567299 | 7.39E-26 |
| KANK2 | 218418_s_at | 0.880372051 | No | 1.084421 | 2E-20 |
| AOC3 | 204894_s_at | 0.880033125 | No | 1.91461 | 3.38E-27 |
| CSRP1 | 200621_at | 0.877492479 | No | 1.134281 | 1.7E-20 |
| PPP1R12B | 201957_at | 0.872867041 | No | 1.795588 | 1.33E-33 |
| PLN | 204940_at | 0.871769799 | No | 2.168066 | 4.12E-24 |
| SYNM | 212730_at | 0.858816617 | No | 2.828553 | 1.48E-26 |
| PDLIM3 | 209621_s_at | 0.839725447 | No | 1.494531 | 3.86E-14 |
| FERMT2 | 214212_x_at | 0.808484526 | No | 0.804553 | 9.87E-12 |
Abbreviations: CRC, colorectal cancer; PPI, protein-protein interaction; DEG, differentially expressed gene; FC, fold change; FDR, false discovery rate.