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. 2020 Feb 3;11(8):2234–2240. doi: 10.7150/jca.38752

Table 3.

Probabilities of MMR and DMR at 12, 18 months by combining observations of the BCR/ABL1IS and halving time at 3 months

G V No. MMR at 12 months P DMR at 12 months P MMR at 18 months P DMR at 18 months P
1 IS ≤10% and HT ≤40 d 35 31(88.6%) <0.001* 7(20%) 0.314* 32(91.4%) <0.001* 15(42.9%) 0.018*
2 IS ≤10% and HT >40 d 9 1(11.1%) 0(0%) 1(11.1%) 0(0%)
3 IS >10% and HT ≤40 d 12 9(75%) <0.001# 3(25%) 0.034# 8(66.7%) 0.001# 2(16.7%) 0.266#
4 IS >10% and HT >40 d 23 0(0%) 0(0%) 2(8.7%) 1(4.3%)

Notes: *P value calculated for Group 1 versus Group 2, #P value calculated for Group 3 versus Group 4. Abbreviations: G: group, V: variable, No.: number, MMR: major molecular response, DMR: deep molecular response, P: p value, HT: the halving time, d: days