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. 2020 Mar 2;11:93. doi: 10.1186/s13287-020-01594-x

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© The Author(s) 2020

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — The miRNA differential expression profiles in EVs. a The histogram showed the differentially expressed miRNAs in CBA-EVs and MRL-EVs. Compared with CBA-EVs, the red histogram represent upregulation for the MRL-EVs, and the black histogram represent downregulation of expression for the MRL-EVs. b The heatmap of top 20 differentially expressed miRNAs in CBA-EVs and MRL-EVs based on miRNA sequence analysis