Table 2.
Comparisons of variables between patients with gout and patients with asymptomatic hyperuricemia
| Variable | Gout (n = 653) | Asymptomatic hyperuricemia (n = 63) | p |
|---|---|---|---|
| Demographic and clinical characteristics | |||
| Male, n (%) | 553 (84.7) | 51 (81.0) | 0.436 a |
| Age (years) | 48.3 ± 15.8 | 43.3 ± 17.9 | 0.018*b |
| ≤30 | 84 | 20 | |
| 31–50 | 290 | 22 | |
| 51–70 | 214 | 15 | |
| 71–90 | 65 | 6 | |
| BMI (kg/ m2) | 24.2 (21.8–26.9) | 23.9 (21.7–27.2) | 0.582 c |
| Age of hyperuricemia onset (years) | 40.7 ± 15.6 | 36.2 ± 17.8 | 0.565 b |
| Hyperuricemia duration (years) | 6.0 (2.0–12.0) | 6.0 (2.0–11.0) | 0.935 c |
| Hypertension, n (%) | 170 (26.0) | 12 (19.0) | 0.224 a |
| Coronary heart disease, n (%) | 67 (10.3) | 5 (7.9) | 0.558 a |
| Laboratory testing | |||
| AST (U/L) | 22.0 (17.6–27.6) | 22.0 (17.2–25.8) | 0.958 c |
| ALT(U/L) | 24.0 (16.0–38.6) | 23.8 (15.9–32.8) | 0.343 c |
| TP(g/L) | 73.9 (70.0–77.7) | 74.6 (71.9–77.8) | 0.519 c |
| ALB(g/L) | 44.3 (40.9–46.8) | 45.5 (41.6–48.8) | 0.095 c |
| TB (μmol/L) | 13.1 (9.6–17.3) | 16.2 (10.9–20.0) | 0.078 c |
| BUN (mmol/L) | 4.85 (4.0–6.2) | 4.9 (4.1–6.5) | 0.678 c |
| Serum creatine (mmol/L) | 90.0 (78.0–106.2) | 83.9 (72.1–103.4) | 0.036*c |
| sUA (μmol/L) | 513.0 (376.5–602.0) | 515.0 (438.0–592.0) | 0.471 c |
| Glucose (mmol/L) | 5.23 (4.80–5.96) | 5.23 (4.70–6.23) | 0.959 c |
| TC (mmol/L) | 5.1 ± 1.1 | 4.7 ± 1.0 | 0.020*b |
| TG (mmol/L) | 1.61 (1.12–2.45) | 1.80 (1.06–2.67) | 0.959 c |
| HDL-C (mmol/L) | 1.14 (0.97–1.39) | 1.14 (0.99–1.36) | 0.975 c |
| LDL-C (mmol/L) | 3.27 (2.62–3.87) | 3.05 (2.39–3.70) | 0.126 b |
| ESR (mm/h) | 31.0 (15.0–54.0) | 21.0 (14.3–30.5) | 0.066 c |
| CRP (mg/L) | 6.53 (4.71–25.1) | 4.95 (4.50–10.3) | 0.040*c |
BMI body mass index, AST aspartate transaminase, ALT alanine aminotransferase, TP total protein, ALB albumin, TB Total bilirubin, BUN blood urea nitrogen, sUA serum uric acid, TC total cholesterol, TG triglycerides, HDL-C high-density lipoprotein, LDL-C Low-density lipoprotein, ESR erythrocyte sedimentation rate, CRP C-reactive protein; a Chi-squared test, b Student’s t test, c Mann Whitney U test were used for the significance of difference between two groups. * p < 0.05