Table 4.
List of rAAVs with average titers in the media
| rAAV Name | Mutations | Average titer in Media (vg/mL) | Source |
|---|---|---|---|
| rAAV2/1 | 8.7E+ 10 | Plasmid Factory | |
| rAAV2/2 | 7.2E+ 10 | Plasmid Factory | |
| rAAV2/3 | 3.5E+ 11 | National Gene Vector Biorepository | |
| rAAV2/4 | 3.6E+ 11 | National Gene Vector Biorepository | |
| rAAV2/5 | 4.7E+ 10 | PlasmidFactory | |
| rAAV2/6 | 4.9E+ 11 | Plasmid Factory | |
| rAAV2/7 | 2.0E+ 11 | Provided by Sergei Zolotukhin, Ph.D., University of Florida | |
| rAAV2/8 | 6.3E+ 11 | PlasmidFactory | |
| rAAV2/9 | 4.2E+ 11 | Provided by Sergei Zolotukhin, Ph.D., University of Florida | |
| rAAV2/Rh10 | 2.4E+ 11 | Provided by Christian Mueller, Ph.D., University of Massachusetts | |
| rAAV2/12 | 5.1E+ 10 | Capsid gene provided by John A. Chiorini, Ph.D., NIH | |
| rAAV2/13 | 6.8E+ 10 | Capsid gene provided by John A. Chiorini, Ph.D., NIH | |
| rAAV2/Bovine | 2.1E+ 11 | Capsid gene provided by John A. Chiorini, Ph.D., NIH | |
| rAAV2/Avian | 5.2E+ 10 | Capsid gene provided by John A. Chiorini, Ph.D., NIH | |
| rAAV2/1-2Y + T | T492V + Y705F + Y731F | 9.5E+ 11 | Provided by Arun Srivastava, Ph.D., University of Florida |
| rAAV2/2-3Y | Y444F + Y500F + Y730F | 3.6E+ 11 | Provided by Shannon E. Boye, PH.D., University of Florida |
| rAAV2/2-4Y | Y272F + Y444F + Y500F + Y730F | 3.2E+ 11 | Provided by Shannon E. Boye, PH.D., University of Florida |
| rAAV2/2-5Y | Y272F + Y444F + Y500F + Y704F + Y730F | 1.5E+ 11 | Provided by Shannon E. Boye, PH.D., University of Florida |
| rAAV2/2-4Y + T + K | Y272F + Y444F + Y500F + Y730F + T491V + K556R | 3.6E+ 11 | Provided by Shannon E. Boye, PH.D., University of Florida |
| rAAV2/5-Y | Y719F | 2.1E+ 11 | Provided by Shannon E. Boye, PH.D., University of Florida |
| rAAV2/5-2Y | Y263F + Y719F | 3.1E+ 11 | Provided by Shannon E. Boye, PH.D., University of Florida |
| rAAV2/6-T + S | T492V + S663V | 7.8E+ 11 | Provided by Arun Srivastava, Ph.D., University of Florida |
| rAAV2/6-2Y + T | T492V + Y705F + Y731F | 5.0E+ 11 | Provided by Arun Srivastava, Ph.D., University of Florida |
| rAAV2/6-2S | S663V + S551V | 6.7E+ 11 | Provided by Arun Srivastava, Ph.D., University of Florida |
| rAAV2/8-Y | Y733F | 2.0E+ 12 | Provided by Shannon E. Boye, PH.D., University of Florida |
| rAAV2/8-2Y | Y447F + Y733F | 2.0E+ 12 | Provided by Shannon E. Boye, PH.D., University of Florida |
| rAAV2/8-3Y | Y275F + Y447F + Y733F | 1.3E+ 12 | Provided by Shannon E. Boye, PH.D., University of Florida |
| rAAV2/8-2Y + T | Y447F + T494V + Y733F | 1.3E+ 12 | Provided by Shannon E. Boye, PH.D., University of Florida |
| rAAV2/9-PHP.B | Insertion at AA588 (TLAVPFKA) | 2.0E+ 11 | Synthesized from Genscript based on reference (21) |
| rAAV2/9-PHP.eB | A587D + Q588G and insertion at AA588 (TLAVPFKA) | 3.8E+ 11 | Synthesized from Genscript based on reference (21) |