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. 2020 Mar 2;19:53. doi: 10.1186/s12934-020-01316-1

Fig. 2.

Fig. 2

Antibody response detected by ELISA and Hemagglutination inhibition (HI) assay. a HA - specific IgG titers. b HI titers. c The cellular immune responses were assayed by ELISpot assay. Splenocytes derived from vaccination (n = 3/group) were incubated on the IFN-γ or IL-4 capture antibody coated with stimulation of HA peptide. IFN-γ and IL-4 spots were counted. The data are presented as mean ± standard deviation (SD). Asterisk indicates statistical significance compared to S.cerevisiae EBY100/pYD5 and PBS groups (p < 0.05)