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. Author manuscript; available in PMC: 2020 Mar 3.
Published in final edited form as: ACS Nano. 2019 Oct 11;13(10):11034–11048. doi: 10.1021/acsnano.9b02807

Figure 9.

Figure 9.

(A) Formation of placental barrier-like junction in JEG-3 cells as confirmed by measuring the TEER and intact TEER after addition of NPs. (B) Quantification of NPs in the apical side, inside the cells, and the basolateral sides of the barrier. (C) Expression of ZO-1 by immunofluorescence. (D) Cellular toxicity of ivermectin and the NPs by performing mitochondrial respiration profiles of JEG-3 cells using MitoStress assay. The cells were treated with the test articles for 24 h at a concentration of 10 μM with respect to ivermectin.