Figure 4.

Biodistribution studies of ¹²⁵I-DCIBzL (18.5 MBq) in mice bearing PSMA+ PC3 PIP and PSMA- PC3 flu tumors show increased uptake in PSMA+ PIP tumors compared to kidneys and PSMA- flu tumors over 3 weeks. The PIP tumor:kidney ratio remained at 2-3:1 during this period. Note that kidney uptake at 1 hr and 24 hrs was too high to be evaluated by γ-counter. Values represent mean ± standard deviation. P<0.05 between PIP tumor and kidney at 2 weeks via t-test, non-significant at other time points.