Figure 5.

(A) Diagram of behavioral procedure. (B) Mean (+SEM) Social exploration the day after stress was reduced compared to baseline in rats injected i.p. with either vehicle or KML29 prior to stress. (C) Mean (+SEM with individual replicates) social exploration expressed as percent of baseline. KML at 40mg/Kg exacerbated the stress induced deficit in social behavior compared to animals that received vehicle prior to stress (p<0.05). *,**, and *** denotes p<0.05, p<0.01, and p<0.001 respectively with Sidak’s post hoc (B) or Tukey’s post hoc (C).