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Upsampled simulated healthy N-acetylaspartate (NAA) and D-2-hydroxyglutarate (D-2HG) metabolite maps. From left to right, images were obtained with high-resolution T1-weighted MRI (matrix, 138 × 138 × 40) magnetization-prepared rapid gradient-echo (MPRAGE) and high-resolution (HR) (matrix, 138 × 138 × 40; ground truth), low-resolution (LR) (matrix, 46 × 46 × 10), and super-resolution (SR) (matrix, 138 × 138 × 40) MR spectroscopy.
