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. 2020 Jan 7;294(3):589–597. doi: 10.1148/radiol.2020191529

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2020 by the Radiological Society of North America, Inc.

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Figure 2: — Upsampled D-2-hydroxyglutarate (D-2HG) and total N-acetylaspartate (NAA) maps of the phantom. From left to right, images were obtained with high-spatial-resolution T1-weighted MRI magnetization-prepared rapid gradient-echo (MPRAGE) (matrix, 138 × 138), low-resolution (LR) total MR spectroscopy (matrix, 46 × 46), upsampled MR spectroscopy with spline interpolation (Spline), upsampled MR spectroscopy with weighted total variation (wTV), super-resolution (SR) MR spectroscopy with spline interpolation and the feature-based nonlocal means method (Spline + FNLM) or SR MR spectroscopy with weighted total variation and FNLM (wTV + FNLM). The numbers on MPRAGE images indicate D-2HG and NAA concentrations in each compartment.