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. 2020 Feb 5;14(3):504–519. doi: 10.1002/1878-0261.12621

Figure 5.

Figure 5

NOTCH pathways genes are more frequently altered in IBC than in non‐IBC. (A) Plot showing the percentage of patients with AGAs involved in the NOTCH pathway in IBC vs non‐IBC patients. The P‐values are for the logit link in univariate analysis and in MV. Beside the plot, are indicated the nine genes common to the pathway in the indicated bibliographic source and to our list of 756 genes tested. (B) Left: Box‐plot of NOTCH activation score in the breast cancer samples of the International IBC Consortium dataset according to the molecular subtypes. The P‐value is for the one‐way ANOVA test. Right: Box‐plot of NOTCH activation score in the breast cancer samples of the International IBC Consortium dataset according to the non‐IBC and IBC statutes. The P‐value is for the Student's t‐test.