Table 7.
Comparison of age, gender, ethnicity, and level of education with severity rating of potential drug-drug interaction in patients admitted for renal dysfunction
| Characteristics | Severity and prevalence of potential DDI (%) |
|||||
|---|---|---|---|---|---|---|
| Contraindication | Major | Moderate | Minor | χ2 | P | |
| Age group | ||||||
| <30 | 0 (0.0) | 13.3 (18) | 66.7 (27.0) | 20 (3.0) | 1.562 | 0.1 |
| 31-40 | 0 (0.0) | 18 (37.50) | 27 (56.30) | 3 (6.30) | ||
| 41-50 | 0 (0.0) | 8 (57.10) | 6 (42.90) | 0 (0.0) | ||
| 51-60 | 0 (0.0) | 7 (15.60) | 34 (75.6) | 4 (8.90) | ||
| >60 | 1 (1.0) | 25 (24.0) | 71 (68.30) | 7 (6.70) | ||
| Gender | ||||||
| Female | 0 (0.0) | 33 (27.3) | 78 (64.5) | 10 (8.3) | 1.436 | 0.697 |
| Male | 1 (1.0) | 27 (25.7) | 70 (66.7) | 7 (6.7) | ||
| Ethnicity | ||||||
| Igbo | 0 (0.0) | 20 (27.8) | 45 (62.5) | 7 (9.7) | 3.339 | 0.765 |
| Yoruba | 0 (0.0) | 23 (26.7) | 57 (66.3) | 5 (5.8) | ||
| Others | 1 (1.4) | 17 (24.6) | 46 (66.7) | 5 (7.2) | ||
| Education | ||||||
| Primary | 0 (0.0) | 1 (7.7) | 11 (84.6) | 1 (7.7) | 4.929 | 0.553 |
| Secondary | 0 (0.0) | 40 (28.4) | 91 (64.50) | 10 (7.10) | ||
| Tertiary | 1 (1.40) | 19 (26.40) | 46 (63.90) | 6 (8.30) | ||
Age, gender, ethnicity, and level of education were not significantly associated with the severity of DDI in patients admitted with renal dysfunction. DDI – Drug–drug interaction; EER – Exposure/exposed ratio