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Effects of VA (10, 20, and 40 mg/kg) and DEX on cardiac TLR4 levels in DOX-induced cardiotoxicity. Values are mean ± SEM; n = 6. ###P < 0.001 Indicates significant differences compared with NS as control group; and *P < 0.05 and ***P < 0.001 versus DOX group. VA, Vanillic acid; DEX, dexrazoxane; DOX, doxorubicin; NS, normal saline; TLR4, toll-like receptor4.
