Table 3.
Associations of genotypic distribution of metastasis-associated in colon cancer-1 gene with clinicopathological characteristics of the patients with invasive cancer of uterine cervix
| rs975263 | ||||
|---|---|---|---|---|
| Variablesa | AA/AGb | GG | p value | ORs (95% CIs) |
| Clinical stage | 1.000 | |||
| stage Ib | 74 | 3 | 1.00 | |
| ≥ stage II | 50 | 2 | 0.99 (0.08-8.94) | |
| Pathologic type | 0.534 | |||
| squamous cell carcinomab | 107 | 4 | 1.00 | |
| adenocarcinoma | 17 | 1 | 1.57 (0.03-17.14) | |
| Cell grading | 0.555 | |||
| well (grade 1)b | 18 | 1 | 1.00 | |
| moderate & poor (grades 2/3) | 106 | 4 | 0.68 (0.06-35.29) | |
| Stromal invasion depth | 1.000 | |||
| ≤10 mmb | 63 | 2 | 1.00 | |
| >10 mm | 56 | 2 | 1.13 (0.08-15.98) | |
| Tumor diameterb | 1.000 | |||
| ≤ 4cm | 68 | 3 | 1.00 | |
| >4cm | 56 | 2 | 0.81 (0.07-7.34) | |
| Parametrium | 1.000 | |||
| no invasionb | 83 | 3 | 1.00 | |
| invasion | 44 | 2 | 1.26 (0.10-11.39) | |
| Vagina | 0.042 | |||
| no invasionb | 87 | 1 | 1.00 | |
| invasion | 40 | 4 | 8.70 (0.81-433.22) | |
| Pelvic lymph node | 0.335 | |||
| no metastasisb | 95 | 5 | 1.00 | |
| metastasis | 32 | 0 | u.a. | |
Statistical analyses: chi-square or Fisher's exact tests. aSome clinicopathological data could not be obtained from the patients with cervical invasive cancer due to incomplete medical charts or records. bAs a reference. ORs, odds ratios; 95% CIs, 95% confidence intervals; u.a., unavailable