Table 5.
Multivariate analysis for impact of metastasis-associated in colon cancer-1 gene polymorphisms and various clinicopatholgical parameters on the 5 years survival rate of the patients with uterine cervical cancer
| 5 years survival hazard | ||
|---|---|---|
| Variables | p value | HR & 95% CIb |
| metastasis-associated in colon cancer-1 gene polymorphisms | ||
| rs975263 | ||
| AG/GG vs AAa | 0.763 | 0.59 (0.02-17.88) |
| GG vs AA/AGa | 0.978 | u.a. |
| rs3095007 | ||
| GT/TT vs GGa | 0.805 | 0.63 (0.02-25.69) |
| TT vs GG/GTa | 0.933 | u.a. |
| rs4721888 | ||
| GC/CC vs GGa | 0.509 | 1.50 (0.45-4.93) |
| CC vs GG/GCa | 0.848 | 1.39 (0.09-18.67) |
| rs3735615 | ||
| GC/CC vs GGa | 0.542 | 0.32 (0.01-12.08) |
| CC vs GG/GCa | u.a. | u.a. |
| rs1990172 | ||
| CA/AA vs CCa | 0.653 | 2.43 (0.05-116.11) |
| AA vs CC/CAa | 0.996 | u.a. |
| Pelvic lymph node | ||
| metastasis vs no metastasisa | 0.001 | 9.98 (2.64-37.77) |
Statistical analyses: Cox proportional hazard model. aAs a comparison reference. bHR, hazard ratio and 95% CI, 95% confidence interval for metastasis-associated in colon cancer-1 genetic variants and clinicopathological variables, compared to their respective controls. u.a., unavailable