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. 2020 Jan 30;16(6):970–980. doi: 10.7150/ijbs.39015

Figure 2.

Figure 2

Longitudinal histologic analysis of cartilage degradation and subchondral bone sclerosis induced by DMM surgery. (A) Alcian blue/Hematoxylin and Orange G staining of the coronal sections of the knee joints collected at different time points as indicated. Black arrow, cartilage degradation. Green arrow, subchondral bone sclerosis. Scale bar, 50 μm. n = 5. (B) Alcian blue/Hematoxylin Orange G staining of the coronal sections of the joints collected 4 weeks after surgery. Black arrow, cartilage degradation. White arrow, subchondral bone sclerosis in the medial tibiae. Red arrow, subchondral bone loss in the lateral tibiae. L, lateral tibiae; M, medial tibiae. Scale bar, 200 μm. n = 5.