Table 1.

Effects of tert-butyl hydroperoxide (t-BHP) on body weight and morphometric parameters of thoracic aorta from young and mature adult rats.

		t-BHP (mmol/kg BW)
Group	Cont	0.1	0.2	0.4
Young (6-week-old)
Body weight
Baseline (g)	159.6±2.0	158.9±0.9	158.5±3.4	159.2±3.3
Final (g)	253.5±3.0	252.4±4.7	238.6±4.7*	243.1±5.2
Weight Gain (%)	59.1±2.3	59.1±2.7	50.7±2.2*	52.9±2.5
Thoracic aorta
Radius (mm)	2.47±0.11	2.64±0.12	2.33±0.07	2.38±0.09
Intima-medial thickness (μm)	174.2±5.4	175.5±12.8	146.0±3.1*	149.4±1.4*
Mature adult (24-week-old)
Body weight
Baseline (g)	471.5±4.5	470.7±4.3	470.8±2.5	473.0±2.8
Final (g)	557.3±4.0	576.7±6.1	563.5±10.6	534.6±6.1*
Weight Gain (%)	18.2±0.7	22.6±1.7	19.7±2.3	13.1±1.4*
Thoracic aorta
Radius (mm)	2.87±0.05	2.73±0.08	2.71±0.01	2.96±0.06
Intima-medial thickness (μm)	189.3±0.5	199.3±0.5**	200.0±2.4*	202.7±2.5*

Representative values are shown as mean ± S.E.M., (Young group, n=12; Mature adult group, n=6); *p<0.05 and **p<0.01, compared to the Cont group.