Table 3.

CI and dose reduction values for inhibition on A549, H1957 and PC9 by combining doxorubicin with apatinib

% Inhibition	CI	Doxorubicin				Apatinib
		Conc.:(μmol/L)		Dose reduction		Conc.:(μmol/L)		Dose reduction
		Alone	Mix			Alone	Mix
A549
50	0.8545	0.784	0.523	1.499		28.998	4.445	6.523
75	1.0332	1.245	0.971	1.282		39.449	8.162	4.833
95	0.9853	1.879	1.435	1.309		54.518	12.751	4.276
NCI-H1975
50	0.5675	0.872	0.231	3.775		13.193	1.242	10.622
75	0.6121	1.411	0.476	2.964		23.643	4.116	5.744
95	0.6798	1.942	0.712	2.728		39.532	5.532	7.146
PC9
50	1.1964	0.214	0.201	1.209		24.682	1.888	13.073
75	1.0532	0.387	0.329	1.294		38.784	2.843	13.641
95	1.1723	0.512	0.483	1.270		51.343	4.032	12.733