Table 1.

Dosing Strategies of Long-Acting Injectable Antipsychotics Currently Available on the Market

Medication	Dosing	Frequency	Notes
Aripiprazole monohydrate	300 mg, 400 mg	Every 4 weeks	14 consecutive days of concurrent oral aripiprazole is recommended.
Aripiprazole lauroxil	441 mg, 662 mg, 882 mg, 1064mg	Every 4–8 weeks	21 consecutive days of concurrent oral aripiprazole or 1 day of oral aripiprazole overlap with Aristada Initio® (aripiprazole lauroxil) is recommended.
Haloperidol decanoate	10-20x daily oral dose	Every 4 weeks	Oral overlap recommended for the first 2 to 3 injections if not using loading dose.
Paliperidone palmitate	39 mg, 78 mg, 117 mg, 156mg, 234 mg	Every 4 weeks	Oral overlap not required but loading doses must be given on days 1 and 8.
Paliperidone palmitate	273 mg, 410 mg, 546 mg, 819 mg	Every 12 weeks	Oral overlap not required but use of once monthly paliperidone palmitate for 4 months is required.
Risperidone (SQ injection)	90 mg, 120 mg	Every 4 weeks	Oral overlap not required.
Fluphenazine decanoate	12.5 mg, 25 mg	Every 2–6 weeks	Oral overlap recommended.
Risperidone (IM injection)	12.5 mg, 25 mg, 37.5 mg, 50 mg	Every 2 weeks	Oral overlap for 3 weeks required.
Olanzapine pamoate	150 mg, 210 mg, 300 mg, 405 mg	Every 2–4 weeks	Monitoring required for 3 hrs post injection due to post-injection delirium/sedation syndrome.