Skip to main content
. Author manuscript; available in PMC: 2020 Mar 3.
Published in final edited form as: Cell Rep. 2020 Feb 11;30(6):1753–1766.e6. doi: 10.1016/j.celrep.2020.01.035

Figure 4. Inulin Controls Colon Cancer Growth and Induces Anti-tumor Immunity.

Figure 4.

(A) Growth of MC-38 mouse colorectal cancer cells (1 × 106) injected subcutaneously into syngeneic C57BL/6 mice that received control diet, 3% mucin in drinking water, or 15% inulin-supplemented chow starting 14 days before tumor inoculation (control, n = 9; mucin, n = 15; inulin, n = 15).

(B) MFI of MHC class II and MHC class I in MC-38 tumor-infiltrating DCs (n = 8).

(C) Boxplot of the relative abundance of the taxa enriched in inulin-treated mice and positively correlated with tumor size (n = 10).

Data are representative of two independent experiments. Graphs show the mean ± SEM. *p < 0.05, **p < 0.005, ***p < 0.001, ****p < 0.0001 by one-way ANOVA with Bonferroni’s correction (B) or by two-way ANOVA with Tukey’s correction (A).