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. 2020 Feb 25;7:46. doi: 10.3389/fmed.2020.00046

Table 3.

Clinical course among the four Clusters (Cluster 1, n = 199; Cluster 2, n = 99; Cluster 3, n = 53; and Cluster 4, n = 25).

Cluster 1 (n = 199) Cluster 2 (n = 99) Cluster 3 (n = 53) Cluster 4 (n = 25) P-values
P (1 vs. 2) P (2 vs. 3) P (3 vs. 4)
SURGICAL INTERVENTIONS WITHIN 24 H
Interventions within 24 h, n (%) 64 (32%) 57 (59%) 34 (64%) 16 (64%) <0.001s 0.57 0.99
Laparotomy, n (%) 16 (8%) 27 (28%) 18 (34%) 10 (40%) <0.001s 0.43 0.60
Orthopedic, n (%) 50 (25%) 46 (47%) 26 (49%) 11 (44%) <0.001s 0.85 0.68
Vascular, n (%) 7 (4%) 12 (12%) 4 (8%) 8 (32%) 0.004s 0.36 0.02s
Craniotomy, n (%) 8 (4%) 4 (4%) 4 (8%) 0 (0%) 0.51
Thoracic, n (%) 2 (1%) 5 (5%) 3 (6%) 4 (16%) 0.04s 1 0.20
BLOOD TRANSFUSION WITHIN 24 H
Blood transfusion, n (%) 33 (17%) 34 (34%) 25 (47%) 13 (52%) 0.001s 0.12 0.69
PRBC 782 ± 157 1906 ± 352 2061 ± 615 3381 ± 427 0.003s 1 0.01s
FFP 805 ± 309 998 ± 248 1070 ± 364 2695 ± 698 1 1 0.03s
CLINICAL OUTCOMES
ICU LOS, days 3.8 ± 0.3 9.9 ± 0.8 14.5 ± 1.2 18.2 ± 1.8 <0.001s <0.001s 0.09
Total LOS, days 9.8 ± 0.4 16.5 ± 1.0 21.8 ± 1.2 26.2 ± 2.1 <0.001s 0.001s 0.11
Mechanical ventilation, days 0.9 ± 0.2 5.5 ± 0.7 8.5 ± 1.0 13.3 ± 1.9 <0.001s 0.01s 0.002s
Nosocomial infection, n (%) 32 (16%) 41 (41%) 26 (49%) 19 (76%) <0.001s 0.37 0.03s
Home-destination, n (%) 111 (56%) 34 (34%) 14 (26%) 5 (20%) <0.001s 0.32 0.54

Values are expressed as either n (%) or mean ± SEM.

Fisher exact test or One-Way ANOVA used as appropriate with statistical significance set at

s

P < 0.05.