TABLE 2.
Cox proportional hazard ratios for the time to first CVD event based on traditional risk factors and MRA at dialysis start.
| Unadjusted | Adjusted* | |||||
| HR | 95% CI | P-value | HR | 95% CI | P-value | |
| Age—years | 1.03 | 1.01, 1.05 | 0.008 | 0.99 | 0.95, 1.03 | 0.6 |
| HDL-cholesterol—mg/dL | 0.99 | 0.97, 1.01 | 0.2 | 0.98 | 0.95, 1.01 | 0.2 |
| Hypertension | 4.77 | 1.14, 19.94 | 0.03 | 7.46 | 1.36, 40.87 | 0.02 |
| Diabetes | 3.02 | 1.53, 5.99 | 0.002 | 2.31 | 0.85, 6.27 | 0.1 |
| CHD history | 2.79 | 1.21, 6.42 | 0.02 | 2.01 | 0.61, 6.59 | 0.3 |
| Body-mass index—kg/m2 | 1.09 | 1.02, 1.15 | 0.005 | 0.90 | 0.79, 1.02 | 0.09 |
| Urine volume—mL | 1.00 | 1.00, 1.00 | 0.9 | 1.00 | 1.00, 1.00 | 0.05 |
| Plasma hsCRP—mg/dL | 1.12 | 1.05, 1.19 | <0.001 | 1.18 | 1.06, 1.32 | 0.003 |
| MRA—HU | 0.94 | 0.91, 0.98 | 0.004 | 0.91 | 0.86, 0.97 | 0.006 |
*Adjusted HR was calculated by integrating age, HDL-cholesterol, hypertension, diabetes, CHD history, body-mass index, residual urine volume, plasma hsCRP, and MRA. Log likelihood = -70.66. HR, hazard ratio; CI, confidence interval; CVD, cardiovascular disease; HDL, high density lipoprotein; CHD, coronary heart disease; hsCRP, high-sensitivity C-reactive protein; MRA, muscle radiation attenuation; HU, Hounsfield units.