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. Author manuscript; available in PMC: 2020 Mar 3.
Published in final edited form as: Dig Dis Sci. 2018 Mar 9;63(5):1311–1319. doi: 10.1007/s10620-018-5009-4

Table 5.

Analysis of factors associated with complete eradication of dysplasia in Barrett’s esophagus

Factor Unadjusted analysis Adjusted analysis


OR (95% CI) p-value OR (95% CI) p-value
Age (1 year increment) 0.96 (0.92, 1.01) 0.11
Male versus female gender 1.9 (0.68, 5.5) 0.22
Caucasian race 1.04 (0.12, 9.3) 0.97
Smoking
 Ex-smoker versus non-smoker 0.91 (0.37, 2.2) 0.85
 Current smoker versus non-smoker 0.64 (0.15, 2.7) 0.55
Current alcohol use 3.0 (1.1, 8.0) 0.027
Body mass index 1.01 (0.94, 1.08) 0.82
Aspirin 2.0 (0.83, 5.0) 0.12
NSAIDs 6.8 (0.86, 883.1) 0.2
Statins 1.2 (0.50, 2.7) 0.71
Proton pump inhibitors 1.6 (0.01, 30.4) 0.84
H2 blockers 0.04 (0.00, 0.49) 0.089
Hypertension 0.50 (0.20, 1.2) 0.14
Diabetes 0.70 (0.25, 2.0) 0.5
Hyperlipidemia 1.7 (0.70, 3.9) 0.26
History of fundoplication 0.29 (0.05, 1.8) 0.19
Length of Barrett’s segment (cm) 0.90 (0.80, 1.02) 0.092
Size of hiatal hernia (cm) 0.92 (0.73, 1.2) 0.46
Baseline biopsy
 Cancer versus dysplasia 0.21 (0.08, 0.52) < 0.001 0.24 (0.09, 0.63) 0.004
RFA versus cryotherapy 1.9 (0.78, 4.6) 0.16 1.7 (0.66, 4.3) 0.28
Num. of treatment sessions 1.04 (0.85, 1.3) 0.72
Months from baseline to last endoscopy (1 month increment) 1.03 (1.00, 1.05) 0.031 1.03 (1.00, 1.05) 0.039

CI confidence interval, NSAID nonsteroidal anti-inflammatory drugs, OR odds ratio, RFA radiofrequency ablation