TABLE 1.
Baseline characteristics of participants who completed neurodevelopmental follow-up at 18-mo corrected age1
| Characteristics | HMBF (n = 59) | BMBF (n = 50) |
|---|---|---|
| Sex, no. (% female) | 35/59 (59.3) | 28/50 (56.0) |
| Birth weight, mean ± SD, g | 893 ± 210 | 901 ± 192 |
| Gestational age at birth,2 mean ± SD, wk | 27.9 ± 2.7 | 27.7 ± 2.2 |
| Multiple birth status, no. (%) | 21/59 (35.6) | 21/50 (42.0) |
| Small for gestational age, no. (%) | 13/59 (22.0) | 13/50 (26.0) |
| Received antenatal steroids, no. (%) | 51/59 (86.4) | 44/50 (88.0) |
| SNAP-II score,3 mean ± SD | 12.7 ± 11.1 | 13.9 ± 11.4 |
| Apgar score at 5 min, mean ± SD | 7.5 ± 2.0 | 7.3 ± 2.3 |
| Any donor milk intake, no. (%) | 27/59 (45.8) | 33/50 (66.0) |
| Mother's age, mean ± SD, y | 33.0 ± 4.6 | 34.1 ± 6.0 |
| Mother's education, no. (%) | ||
| High school or less | 7/58 (12.1) | 8/50 (16.0) |
| College or vocational diploma | 23/58 (39.7) | 18/50 (36.0) |
| Baccalaureate | 20/58 (34.5) | 15/50 (30.0) |
| Postbaccalaureate | 8/58 (13.8) | 9/50 (18.0) |
| Mother's ethnicity,4 no. (%) | ||
| Eastern or Western European | 24/58 (41.4) | 16/50 (32.0) |
| East or Southeast Asian | 14/58 (24.1) | 12/50 (24.0) |
| South or West Asian | 10/58 (17.2) | 10/50 (20.0) |
| Caribbean | 6/58 (10.3) | 8/50 (16.0) |
| Other | 4/58 (6.9) | 4/50 (8.0) |
| Maternal parity, mean ± SD | 1.5 ± 0.9 | 1.6 ± 0.9 |
| Family living below the poverty line,5 No. (%) | 13/58 (22.4) | 13/50 (26.0) |
| Morbidity composite,6 no. (%) | 20/59 (33.9) | 24/50 (48.0) |
| Brain injury,7 no. (%) | 7/59 (11.9) | 7/50 (14.0) |
Data are expressed as mean ± SD or frequency count (%).
Gestational age determined using maternal estimates of her last menstrual period. If early ultrasound prediction differed by 2 wk or more, the gestational age estimate derived from early ultrasound was used.
Score for Neonatal Acute Physiology II. Scores may range from 0 to 100 with higher values indicating higher neonatal risk and newborn illness.
Other includes African (n = 4), Latin American (n = 1), or mixed-race mothers (n = 3).
Based on 2012 Statistics Canada family size-adjusted cut-off values.
Includes late-onset sepsis, chronic lung disease, necrotizing enterocolitis, and retinopathy of prematurity requiring treatment.
Includes echodense intraparenchymal lesions, periventricular leukomalacia, porencephalic cysts, or ventriculomegaly with or without intraventricular hemorrhage.
BMBF, bovine milk-based fortifier group; HMBF, human milk-based fortifier group; SNAP, score for neonatal acute physiology.