Table 1. Correlation between ZEB1-AS1 expression and clinicopathological characteristics of CCA patients.
| Clinicopathological parameters | Total cases (n = 54) | ZEB1-AS1 expression | P-value | |
| Low (n = 25) | High (n = 29) | |||
| Age (years) | ||||
| < 60 | 17 | 9 | 8 | 0.507 |
| ≥ 60 | 37 | 16 | 21 | |
| Gender | ||||
| Male | 23 | 10 | 13 | 0.721 |
| Female | 31 | 15 | 16 | |
| Tumor location | ||||
| Intrahepatic | 16 | 9 | 7 | 0.341 |
| Extrahepatic | 38 | 16 | 22 | |
| Histological type | ||||
| Adenocarcinoma | 49 | 24 | 25 | 0.216 |
| Non-adenocarcinoma | 5 | 1 | 4 | |
| Differentiation grade | ||||
| Well/moderate | 22 | 13 | 9 | 0.118 |
| Poor/undifferentiated | 32 | 12 | 20 | |
| TNM stage | ||||
| I-II | 24 | 16 | 8 | 0.007** |
| III-IV | 30 | 9 | 21 | |
| Lymph node invasion | ||||
| Yes | 35 | 12 | 23 | 0.016* |
| No | 19 | 13 | 6 | |
| Serum CA19-9 level | ||||
| > 37 U/ml | 34 | 13 | 21 | 0.121 |
| ≤ 37 U/ml | 20 | 12 | 8 | |
Note. *P < 0.05, **P < 0.01. ZEB1-AS1, Zinc finger E-box binding homeobox 1 antisense 1; CCA, cholangiocarcinoma.