Table 4. Multivariate logistic regression analysis for the presence of CVD.
Independent variable | OR (95% CI) | P-value |
Model 1 | ||
Age | 1.086 (1.011 to 1.166) | <0.05 |
Sex | 0.262 (0.075 to 1.914) | 0.19 |
Smoker | 3.216 (1.810 to 12.773) | <0.05 |
HT | 0.814 (0.203 to 3.261) | NS |
DM | 0.773 (0.230 to 2.603) | NS |
Serum cholesterol | 0.988 (0.975 to 1.001) | 0.12 |
eGFR | 0.961 (0.916 to 1.007) | 0.09 |
Model 2 | ||
Age | 1.203 (1.044 to 1.386) | <0.05 |
Sex | 5.313 (0.545 to 51.778) | 0.15 |
Smoker | 55.448 (3.183 to 965.866) | <0.01 |
HT | 0.511 (0.060 to 4.337) | NS |
DM | 0.622 (0.088 to 4.415) | NS |
Serum cholesterol | 0.976 (0.954 to 1.998) | 0.09 |
eGFR | 0.986 (0.926 to 1.051) | NS |
CRP | 1.522 (0.972 to 2.383) | 0.07 |
NLR | 1.804 (1.028 to 3.166) | <0.05 |
TNFα/IL10 | 14.726 (0.945 to 229.372) | 0.06 |
Model 3 | ||
Age | 1.336 (1.059 to 1.685) | <0.05 |
Sex | 7.132 (0.302 to 168.594) | NS |
Smoker | 55.658 (1.543 to 2007.350) | <0.05 |
HT | 0.951 (0.047 to 19.267) | NS |
DM | 3.721 (0.137 to 100.783) | NS |
Serum cholesterol | 0.968 (0.938 to 1.019) | 0.06 |
eGFR | 1.058 (0.965 to 1.159) | NS |
CRP | 1.178 (0.723 to 1.919) | 0.13 |
NLR | 5.524 (1.096 to 31.709) | <0.05 |
TNFα/IL10 | 27.552 (0.608 to 1246.780) | 0.08 |
Klotho | 0.995 (0.991 to 0.998) | <0.01 |
HT, hypertension; DM, diabetes mellitus; eGFR, estimated glomerular filtration rate; CRP, c-reactive protein; NLR, neutrophil-to-lymphocyte ratio; TNFα, tumor necrosis factor- α; IL10, interleukin 10; NS, not significant.