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. 2020 Jan 27;12(2):1952–1964. doi: 10.18632/aging.102734

Table 4. Multivariate logistic regression analysis for the presence of CVD.

Independent variable OR (95% CI) P-value
Model 1
 Age 1.086 (1.011 to 1.166) <0.05
 Sex 0.262 (0.075 to 1.914) 0.19
 Smoker 3.216 (1.810 to 12.773) <0.05
 HT 0.814 (0.203 to 3.261) NS
 DM 0.773 (0.230 to 2.603) NS
 Serum cholesterol 0.988 (0.975 to 1.001) 0.12
 eGFR 0.961 (0.916 to 1.007) 0.09
Model 2
 Age 1.203 (1.044 to 1.386) <0.05
 Sex 5.313 (0.545 to 51.778) 0.15
 Smoker 55.448 (3.183 to 965.866) <0.01
 HT 0.511 (0.060 to 4.337) NS
 DM 0.622 (0.088 to 4.415) NS
 Serum cholesterol 0.976 (0.954 to 1.998) 0.09
 eGFR 0.986 (0.926 to 1.051) NS
 CRP 1.522 (0.972 to 2.383) 0.07
 NLR 1.804 (1.028 to 3.166) <0.05
 TNFα/IL10 14.726 (0.945 to 229.372) 0.06
Model 3
 Age 1.336 (1.059 to 1.685) <0.05
 Sex 7.132 (0.302 to 168.594) NS
 Smoker 55.658 (1.543 to 2007.350) <0.05
 HT 0.951 (0.047 to 19.267) NS
 DM 3.721 (0.137 to 100.783) NS
 Serum cholesterol 0.968 (0.938 to 1.019) 0.06
 eGFR 1.058 (0.965 to 1.159) NS
 CRP 1.178 (0.723 to 1.919) 0.13
 NLR 5.524 (1.096 to 31.709) <0.05
 TNFα/IL10 27.552 (0.608 to 1246.780) 0.08
 Klotho 0.995 (0.991 to 0.998) <0.01

HT, hypertension; DM, diabetes mellitus; eGFR, estimated glomerular filtration rate; CRP, c-reactive protein; NLR, neutrophil-to-lymphocyte ratio; TNFα, tumor necrosis factor- α; IL10, interleukin 10; NS, not significant.